Findings	S. aromaticum	O. sanctum
Toxic Dose	Equal or greater than 1500 mg/kg [98]	55 ml/kg [99]
Maximum Daily Intake	2.5 mg/kg[35]	30 ml/kg [99]
LD50	18.2 ±5.52 mg/ml in Danio rerio and 21.7 ±0.8 mg/ml in Poecilia reticulata at 96h[100]	42.5 ml/kg 99]
Adverse Reaction	Spermicidal activity in males, allergic action when used in dentistry, increased endogenous redox enzyme levels and Reduced lipid peroxidation in humans resulted in disseminated intravascular coagulopathy, generalized seizures, and hepatotoxicity, detoxification, and cardiac health effects, allergic contact dermatitis in guinea pigs[98] [101]	Clinical trial reporting transient moderate nausea [102]